Women with endometriosis face 46% higher risk of type 2 diabetes, study finds

Largest examine so far inspecting the connection between the 2 situations

Our findings add to a rising understanding that endometriosis might have an effect on greater than reproductive well being alone.”

— Maggie Fuzak Nunziato

FAIRFAX, VA, UNITED STATES, August 10, 2026 /EINPresswire.com/ — Ladies with endometriosis have a 46% greater threat of growing sort 2 diabetes than ladies with out the situation, in line with a brand new examine led by researchers on the George Mason Faculty of Public Well being and collaborators.

Following knowledge from practically 3 million ladies over 25 years, the study, published in Diabetologia, is the most important so far inspecting the connection between endometriosis and sort 2 diabetes. Maggie Fuzak Nunziato, a George Mason doctoral scholar in epidemiology, led the analysis with Anna Pollack, professor of World and Group Well being.

Researchers discovered that diabetes threat diversified throughout completely different types of endometriosis, suggesting the situation might have broader long-term well being implications than beforehand acknowledged. They consider the power irritation related to endometriosis might play a task in metabolic well being, although extra analysis is required to know the connection.

“Earlier research largely evaluated endometriosis as a single situation and customarily reported little or no total affiliation with sort 2 diabetes,” stated Fuzak Nunziato, the examine’s lead creator. “Our findings add to a rising understanding that endometriosis might have an effect on greater than reproductive well being alone.”

Notably, researchers discovered the affiliation was strongest amongst premenopausal ladies and ladies with out weight problems—teams not historically thought-about on the highest threat for sort 2 diabetes.

Why it issues

Endometriosis impacts about 1 in 10 ladies of reproductive age. It happens when tissue just like the uterine lining grows outdoors the uterus, which may usually trigger power pelvic ache, infertility, and different issues.

If the examine’s findings are confirmed by future analysis, they may assist clinicians determine ladies with endometriosis who could also be at greater threat for sort 2 diabetes and who may benefit from earlier screening or prevention efforts.

Extra examine particulars

The examine analyzed well being data from practically 3 million ladies within the Utah Inhabitants Database between 1996 and 2021, together with practically 100,000 recognized with endometriosis.

Researchers discovered that some types of endometriosis carried a a lot stronger affiliation with diabetes than others. The hyperlink was biggest amongst ladies with extra-pelvic endometriosis, which means the illness is discovered outdoors the pelvis.

The researchers emphasize that the findings present an affiliation, not proof that endometriosis could cause sort 2 diabetes. They are saying extra analysis is required to raised perceive the organic mechanisms connecting the 2 situations, and whether or not earlier metabolic screening might enhance outcomes for girls with endometriosis.

The examine additionally included collaborators from the College of Utah, the College of Arizona, Brigham and Ladies’s Hospital, and Intermountain Well being.

Mary Cunningham
George Mason College Faculty of Public Well being
+ +1 703-993-1931
mcunni7@gmu.edu
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