NASA-backed study finds clue to why astronauts experience constipation

(NewsNation) — Constipation has lengthy been a standard problem for astronauts, with many scientists suspecting that microgravity performs a job in disrupting digestion. Now, researchers from the College of Copenhagen, working with NASA, say they’ve recognized organic markers which will assist clarify why.

The study examined blood samples from 52 astronauts who spent two months or longer aboard the Worldwide Area Station.

“We see adjustments in astronauts’ blood samples that point out that the intestine micro organism begins to ferment protein to a larger extent than typical inside weeks after the astronauts arrive in area, and this alteration continues till they’re again on Earth,” lead creator Giorgia La Barbera, an affiliate professor within the Division of Vitamin, Train and Sports activities, stated in a statement.

Protein fermentation happens when accessible fiber within the intestine is depleted and micro organism start breaking down protein as a substitute. Researchers recognized the adjustments by analyzing blood metabolites, which might present clues about digestive perform and dietary habits.

The researchers stated elevated protein fermentation could also be linked to a number of well being considerations, together with kidney harm, impaired focus and mood-related results.

“The dearth of gravity in area most likely causes meals to maneuver extra slowly by the gut, and this suits with the truth that we’re seeing indicators of elevated protein fermentation,” co-author Henrik Roager, an affiliate professor within the Division of Vitamin, Train and Sports activities, stated. “This will likely additionally assist clarify constipation in astronauts.”

Researchers stated the findings might develop into more and more essential as area businesses plan longer-duration missions deeper into the photo voltaic system.

“Our findings can inform potential interventions, both straight by rising dietary fiber, supplementation with prebiotics or different varieties of therapies that promote peristalsis and reduce intestine transit time,” Roager stated. “This could assist cut back protein fermentation and thus present a wholesome intestine surroundings and keep away from unfavourable well being penalties.”

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